Hellenic Open University (HOU) is a Public University founded by the Greek Government in 1992 and fully operational since 1997. HOU comprises of 4 Schools and offers 31 programmes of study to about 35000 adult students, who are dispersed all over the country. It is the only Greek University that uses the distance learning methodology combined with the principles of adult education. About 80% of its students are working professionals who seek a further education degree in order to improve or change their career. The Educational Content, Methodology and Technology Laboratory (e-CoMeT Lab) (http://eeyem.eap.gr) was established as an independent unit with HOU in 1997. Its primary mission is to support HOU in applying educational, methodological and technological innovation in distance learning and educational content development. In addition, it pursues Research and Innovation activities and participates in national and international consortia and networks of excellence. During the past 5 years, the e-CoMeT Lab employs more than 40 people in research, development and administration activities, having an average annual turnover of around 1ME. e-CoMeT Lab activities evolve around the following axes: • creation (development, production, publishing), access and usage (retrieval and sharing) and maintenance (storage, archiving, adaptation) of educational content and material (in printed or digital format), • development and evolution of distance learning methodologies, by exploiting the contemporary educational and pedagogical theories, as well as the technological developments that ensure their efficient application, and • development or application of modern Information and Communication Technologies (IST) applications to support education. Both HOU and e-CoMeT Lab apply the ISO 9001:2008 quality system.